Western Equine Encephalitis Virus

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Overview:

Recently, the International Health Regulations National Focal Point (IHR NFP) in Argentina alerted the World Health Organization of a human case of Western Equine Encephalitis Virus (WEEV) infection.

About Western Equine Encephalitis Virus: 

  • It is a mosquito-borne infection caused by the Western Equine Encephalitis Virus (WEEV), which belongs to the Togaviridae family of viruses.
  • The virus has an approximately 11.5 kilobases long single-stranded RNA genome.
  • It is a recombinant of the eastern equine encephalitis virus (EEEV) and a Sindbis-like virus.
  • Passerine birds are thought to be the reservoir and equine species as intermediate hosts.
  • The primary mode of transmission of the infection to humans is through mosquitoes which act as vectors for the virus.
  • Symptoms:

o While most of the infections are asymptomatic, the infection may lead to severe consequences in rare cases.

o An estimated 4-5% of cases may manifest as infection/inflammation of the brain, resulting in neurological symptoms and sequelae of disease.

· Treatment: With no specific antiviral treatment, symptomatic care is crucial, especially for neurologic symptoms. 


Q1:What is a virus?

A virus is an infectious microbe consisting of a segment of nucleic acid (either DNA or RNA) surrounded by a protein coat.


Source:Outbreak of Western Equine Encephalitis Virus in Argentina